• NILU's Strategic Institute Initiatives (SIS) 2016 

      Aas, Wenche; Rundén-Pran, Elise; Breivik, Knut; Sundseth, Kyrre; Høiskar, Britt Ann Kåstad; Platt, Stephen Matthew; Castell, Nuria; Schlabach, Martin (NILU report; 12/2017, Research report, 2017)
      Each of NILU’s Strategic Institute Initiatives (SIS) is required to deliver a popular science report annually to the Research Council. This report contains NILU’s final reports for the SIS-projects that ended in 2016, and ...
    • NILU’s Strategic Institute Initiatives (SIS) - 2014 

      Lopez-Aparicio, Susana; Myhre, Cathrine Lund; Fiebig, Markus; Schlabach, Martin; Aas, Wenche; Breivik, Knut; Rundén-Pran, Elise (NILU OR;8/2015, Research report, 2015)
      Each of NILU’s Strategic Institute Initiatives (SIS) is required to deliver a popular science report annually to the Research Council. This report contains all of NILU’s annual SIS-reports for 2014
    • Pharmacokinetics of PEGylated Gold Nanoparticles: In Vitro—In Vivo Correlation 

      Dubaj, Tibor; Kozics, Katarina; Srámková, Monika; Manova, Alena; Bastus, Neus G.; Moriones, Oscar H.; Kohl, Yvonne; Dusinska, Maria; Rundén-Pran, Elise; Puntes, Victor; Nelson, Andrew; Gábelová, Alena; Simon, Peter (Peer reviewed; Journal article, 2022)
      Data suitable for assembling a physiologically-based pharmacokinetic (PBPK) model for nanoparticles (NPs) remain relatively scarce. Therefore, there is a trend in extrapolating the results of in vitro and in silico studies ...
    • Rapid identification of in vitro cell toxicity using an electrochemical membrane screening platform 

      Kohl, Yvonne; William, Nicola; Elje, Elisabeth; Backes, Nadine; Rothbauer, Mario; Srancikova, Annamaria; Rundén-Pran, Elise; El Yamani, Naouale; Korenstein, Rafi; Madi, Lea; Barbul, Alexander; Kozics, Katarina; Sramkova, Monika; Steenson, Karen; Gabelova, Alena; Ertl, Peter; Dusinska, Maria; Nelson, Andrew (Peer reviewed; Journal article, 2023)
      This study compares the performance and output of an electrochemical phospholipid membrane platform against respective in vitro cell-based toxicity testing methods using three toxicants of different biological action ...
    • Recent advances and current challenges of new approach methodologies in developmental and adult neurotoxicity testing 

      Serafini, Melania Maria; Sepheri, Sara; Midali, Miriam; Stinckens, Marth; Biesiekierska, Marta; Wolniakowska, Anna; Gatzios, Alexandra; Rundén-Pran, Elise; Reszka, Edyta; Marinovich, Marina; Vanhaecke, Tamara; Roszak, Joanna; Viviani, Barbara; Tanima, SenGupta (Peer reviewed; Journal article, 2024)
      Adult neurotoxicity (ANT) and developmental neurotoxicity (DNT) assessments aim to understand the adverse effects and underlying mechanisms of toxicants on the human nervous system. In recent years, there has been an ...
    • Safe(r) by design implementation in the nanotechnology industry 

      Jiménes, Araceli Sánchez; Puelles, Raquel; Pérez-Fernández, Marta; Gómez-Fernández, Paloma; Barruetabena, Leire; Jacobsen, Nicklas Raun; Suarez-Merino, Blanca; Micheletti, Christian; Manier, Nicolas; Trouiller, Benedicte; Navas, José Maria; Kalman, Judit; Salieri, Beatrice; Hischier, Roland; Handzhiyski, Yordan; Apostolova, Margarita D.; Hadrup, Niels; Bouillard, Jaques; Oudart, Yohan; Merino, Cesar; Garcia, Erika; Liguori, Biase; Sabella, Stefania; Rose, Jerome; Maison, Armand; Galea, Karen S.; Kelly, Sean; Stepankova, Sandra; Mouneyrac, Catherine; Barrick, Andrew; Chatel, Amelie; Dusinska, Maria; Rundén-Pran, Elise; Mariussen, Espen; Bressot, Christophe; Aguerre-Chariol, Olivier; Shandilya, Neeraj; Goede, Henk; Gomez-Cordon, Julio; Simar, Sophie; Nesslany, Fabrice; Jensen, Keld Alstrup; van Tongeren, Martie; Llopis, Isabel Rodriguez (Peer reviewed; Journal article, 2020)
      The implementation of Safe(r) by Design (SbD) in industrial innovations requires an integrated approach where the human, environmental and economic impact of the SbD measures is evaluated across and throughout the nanomaterial ...
    • Safety-by-design and engineered nanomaterials: the need to move from theory to practice 

      Trump, Benjamin D.; Antunes, Dalila; Palma-Oliveira, José; Nelson, Andrew; Hudecova, Alexandra Misci; Rundén-Pran, Elise; Dusinska, Maria; Gispert, Ignasi; Resch, Susanne; Alfaro-Serrano, Beatriz; Afantitis, Antreas; Melagraki, Georgia; Tse, Edmund C. M.; Trump, Josh; Kohl, Yvonne; Linkov, Igor (Peer reviewed; Journal article, 2023)
      As the governance of engineered nanomaterials (ENMs) evolves, innovations in the prevention, mitigation, management, and transfer of risk shape discussion of how nanotechnology may mature and reach various marketplaces. ...
    • The comet assay applied to HepG2 liver spheroids 

      Elje, Elisabeth; Hesler, Michelle; Rundén-Pran, Elise; Mann, Pascal; Mariussen, Espen; Wagner, Sylvia; Dusinska, Maria; Kohl, Yvonne (Journal article; Peer reviewed, 2019)
      In accordance with the 3 Rs to reduce in vivo testing, more advanced in vitro models, moving from 2D monolayer to 3D cultures, should be developed for prediction of human toxicity of industrial chemicals and environmental ...
    • Thermodynamic parameters at bio-nano interface and nanomaterial toxicity: A case study on BSA interaction with ZnO, SiO2 and TiO2 

      Precupas, Aurica; Gheorghe, Daniela; Botea-Petcu, Alina; Leonties, Anca Ruxandra; Sandu, Romica; Popa, Vlad Tudor; Mariussen, Espen; El Yamani, Naouale; Rundén-Pran, Elise; Dumit, Veronica; Xue, Ying; Cimpan, Mihaela Roxana; Dusinska, Maria; Haase, Andrea; Tanasescu, Speranta (Peer reviewed; Journal article, 2020)
      Understanding nanomaterial (NM)–protein interactions is a key issue in defining the bioreactivity of NMs with great impact for nanosafety. In the present work, the complex phenomena occurring at the bio/nano interface were ...
    • Versailles project on advanced materials and standards (VAMAS) interlaboratory study on measuring the number concentration of colloidal gold nanoparticles 

      Minelli, Caterina; Wywijas, Magdalena; Bartczak, Dorota; Cuello-Nuñez, Susana; Infante, Heidi Goenaga; Deumer, Jerome; Gollwitzer, Christian; Krumrey, Michael; Murphy, Karen E.; Johnson, Monique E.; Bustos, Antonio R. Montoro; Strenge, Ingo H.; Faure, Bertrand; Høghøj, Peter; Tong, Vivian; Burr, Loïc; Norling, Karin; Höök, Fredrik; Roesslein, Matthias; Kocic, Jovana; Hendriks, Lyndsey; Kestens, Vikram; Ramaye, Yannic; Lopez, Maria C. Contreras; Auclair, Guy; Mehn, Dora; Gilliland, Douglas; Potthoff, Annegret; Oelschlägel, Kathrin; Tentschert, Jutta; Jungnickel, Harald; Krause, Benjamin C.; Hachenberger, Yves U.; Reichardt, Philipp; Luch, Andreas; Whittaker, Thomas E.; Stevens, Molly M.; Gupta, Shalini; Singh, Akash; Lin, Fang-Hsin; Liu, Yi-Hung; Costa, Anna Luisa; Baldisserri, Carlo; Jawad, Rid; Andaloussi, Samir E. L.; Holme, Margaret N.; Lee, Tae Geol; Kwak, Minjeong; Kim, Jaeseok; Ziebel, Johanna; Guignard, Cedric; Cambier, Sebastien; Contal, Servane; Gutleb, Arno; Tatarkiewicz, Jan; Jankiewicz, Bartlomiej J.; Bartosewicz, Bartosz; Wu, Xiaochun; Fagan, Jeffrey A.; Elje, Elisabeth; Rundén-Pran, Elise; Dusinska, Maria; Kaur, Inder Preet; Price, David; Nesbitt, Ian; O'Reilly, Sarah; Peters, Ruud J. B.; Bucher, Guillaume; Coleman, Dennis; Harrison, Angela J.; Ghanem, Antoine; Gering, Anne; McCarron, Eileen; Fitzgerald, Niamh; Cornelis, Geert; Tuoriniemi, Jani; Sakai, Midori; Tsuchida, Hidehisa; Maguire, Ciarán; Prina-Mello, Adriele; Lawlor, Alan J.; Adams, Jessica; Schultz, Carolin L.; Constantin, Doru; Thanh, Nguyen Thi Kim; Tung, Le Duc; Panariello, Luca; Damilos, Spyridon; Gavriilidis, Asterios; Lynch, Iseult; Fryer, Benjamin; Quevedo, Ana Carrazco; Guggenheim, Emily; Briffa, Sophie; Valsami-Jones, Eugenia; Huang, Yuxiong; Keller, A.; Kinnunen, Virva-Tuuli; Perämäki, Siiri; Krpetic, Zeljka; Greenwood, Michael; Shard, Alexander G. (Peer reviewed; Journal article, 2022)
      We describe the outcome of a large international interlaboratory study of the measurement of particle number concentration of colloidal nanoparticles, project 10 of the technical working area 34, “Nanoparticle Populations” ...