Browsing NILU Brage by Author "Fessard, Valérie"
Now showing items 1-5 of 5
-
Current status and future challenges of genotoxicity OECD Test Guidelines for nanomaterials: a workshop report
Doak, Shareen H.; Andreoli, Cristina; Burgum, Michael J.; Chaudhry, Qasim; Bleeker, Eric; Bossa, Cecilia; Domenech, Josefa; Drobne, Damjana; Fessard, Valérie; Jeliazkova, Nina; Longhin, Eleonora Marta; Rundén-Pran, Elise; Stepnik, Maciej; El Yamani, Naouale; Catalán, Julia; Dusinska, Maria (Peer reviewed; Journal article, 2023)Genotoxicity testing for nanomaterials remains challenging as standard testing approaches require some adaptation, and further development of nano-specific OECD Test Guidelines (TGs) and Guidance Documents (GDs) are needed. ... -
High throughput toxicity screening and intracellular detection of nanomaterials
Collins, Andrew Richard; Balasubramanyam, Annangi; Rubio, Laura; Marcos, Ricard; Dorn, Marco; Merker, Carolin; Estrela-Lopis, Irina; Cimpan, Mihaela Roxana; Ibrahim, Mohamed; Cimpan, Emil; Ostermann, Melanie; Sauter, Alexander; El Yamani, Naouale; Shaposhnikov, Sergey; Chevillard, Sylvie; Paget, Vincent; Grall, Romain; Delic, Jozo; Goñi- de-Cerio, Felipe; Suarez-Merino, Blanca; Fessard, Valérie; Hogeveen, Kevin N; Fjellsbø, Lise Marie; Rundén-Pran, Elise; Brzicova, Tana; Topinka, Jan; João Silva, Maria; Leite, PE; Ribeiro, AR; Granjeiro, JM; Grafström, Roland; Prina-Mello, Adriele; Dusinska, Maria (Journal article; Peer reviewed, 2017) -
Linking Nanomaterial-Induced Mitochondrial Dysfunction to Existing Adverse Outcome Pathways for Chemicals
Murugadoss, Sivakumar; Vrček, Ivana Vinković; Schaffert, Alexandra; Paparella, Martin; Pem, Barbara; Sosnowska, Anita; Stępnik, Maciej; Martens, Marvin; Willighagen, Egon L.; Puzyn, Tomasz; Cimpan, Mihaela-Roxana; Lemaire, Frauke; Mertens, Birgit; Dusinska, Maria; Fessard, Valérie; Hoet, Peter H. (Peer reviewed; Journal article, 2023)The Adverse Outcome Pathway (AOP) framework plays a crucial role in the paradigm shift of toxicity testing towards the development and use of new approach methodologies. AOPs developed for chemicals are in theory applicable ... -
The miniaturized enzyme-modified comet assay for genotoxicity testing of nanomaterials
El Yamani, Naouale; Rundén-Pran, Elise; Collins, Andrew Richard; Longhin, Eleonora Marta; Elje, Elisabeth; Hoet, Peter; Vrček, Ivana Vinković; Doak, Shareen H.; Fessard, Valérie; Dusinska, Maria (Peer reviewed; Journal article, 2022)The in vitro comet assay is a widely applied method for investigating genotoxicity of chemicals including engineered nanomaterials (NMs). A big challenge in hazard assessment of NMs is possible interference between the NMs ... -
A strategy towards the generation of testable adverse outcome pathways for nanomaterials
Murugadoss, Sivakumar; Vrcek, Ivana Vinkovic; Pem, Barbara; Jagiello, Karolina; Judzinska, Beata; Sosnowska, Anita; Martens, Marvin; Willighagen, Egon L.; Puzyn, Tomasz; Dusinska, Maria; Cimpan, Mihaela-Roxana; Fessard, Valérie; Hoet, Peter H. (Peer reviewed; Journal article, 2021)Manufactured nanomaterials (NMs) are increasingly used in a wide range of industrial applications leading to a constant increase in the market size of nano-enabled products. The increased production and use of NMs are ...