• Decitabine-induced DNA methylation-mediated transcriptomic reprogramming in human breast cancer cell lines; the impact of DCK overexpression 

      Buociková, Verona; Tyciakova, Sylvia; Pilalis, Eleftherios; Mastrokalou, Chara; Urbanova, Maria; Matuskova, Miroslava; Demkova, Lucia; Medova, Veronika; Longhin, Eleonora Marta; Rundén-Pran, Elise; Dusinska, Maria; Rios Mondragon, Ivan; Cimpan, Mihaela-Roxana; Gábelová, Alena; Soltysova, Andrea; Smolkova, Bozena; Chatziioannou, Aristotelis (Peer reviewed; Journal article, 2022)
      Decitabine (DAC), a DNA methyltransferase (DNMT) inhibitor, is tested in combination with conventional anticancer drugs as a treatment option for various solid tumors. Although epigenome modulation provides a promising ...
    • Epigenetics in breast cancer therapy—New strategies and future nanomedicine perspectives 

      Buociková, Verona; Rios Mondragon, Ivan; Pilalis, Eleftherios; Chatziioannou, Aristotelis; Miklíková, Svetlana; Mego, Michal; Pajuste, Karlis; Rucins, Martins; El Yamani, Naouale; Longhin, Eleonora Marte; Sobolev, Arkadij; Freixanet, Muriel; Puntes, Victor; Plotniece, Aiva; Dusinska, Maria; Cimpan, Mihaela Roxana; Gábelová, Alena; Smolková, Božena (Peer reviewed; Journal article, 2020)
      Epigenetic dysregulation has been recognized as a critical factor contributing to the development of resistance against standard chemotherapy and to breast cancer progression via epithelial-to-mesenchymal transition. ...
    • Hazard assessment of nanomaterials: how to meet the requirements for (next generation) risk assessment 

      Longhin, Eleonora Marta; Rios Mondragon, Ivan; Mariussen, Espen; Zheng, Congying; Busquets, Marti; Gajewicz Skrętna, Agnieszka; Hofshagen, Ole-Bendik; Bastus, Neus Gómez; Puntes, Victor Franco; Cimpan, Mihaela-Roxana; Shaposhnikov, Sergey; Dusinska, Maria; Rundén-Pran, Elise (Peer reviewed; Journal article, 2024)
      Background Hazard and risk assessment of nanomaterials (NMs) face challenges due to, among others, the numerous existing nanoforms, discordant data and conflicting results found in the literature, and specific challenges ...