• Are Fluoropolymers Really of Low Concern for Human and Environmental Health and Separate from Other PFAS? 

      Lohmann, Rainer; Cousins, Ian T.; DeWitt, Jamie; Glüge, Juliane; Goldenman, Gretta; Herzke, Dorte; Lindstrom, Andrew B.; Miller, Mark F.; Ng, Carla A.; Patton, Sharyle; Scheringer, Martin; Trier, Xenia; Wang, Zhanyun (Peer reviewed; Journal article, 2020)
      Fluoropolymers are a group of polymers within the class of per- and polyfluoroalkyl substances (PFAS). The objective of this analysis is to evaluate the evidence regarding the environmental and human health impacts of ...
    • Finding essentiality feasible: common questions and misinterpretations concerning the “essential-use” concept 

      Cousins, Ian T.; Dewitt, Jamie C.; Glüge, Juliane; Goldenman, Gretta; Herzke, Dorte; Lohmann, Rainer; Miller, Mark; Ng, Carla A.; Patton, Sharyle; Scheringer, Martin; Trier, Xenia; Wang, Zhanyun (Peer reviewed; Journal article, 2021)
      The essential-use concept is a tool that can guide the phase-out of per- and polyfluoroalkyl substances (PFAS) and potentially other substances of concern. This concept is a novel approach to chemicals management that ...
    • The high persistence of PFAS is sufficient for their management as a chemical class 

      Cousins, Ian T.; Dewitt, Jamie C.; Glüge, Juliane; Goldenman, Gretta; Herzke, Dorte; Lohmann, Rainer; Ng, Carla A.; Scheringer, Martin; Wang, Zhanyun (Peer reviewed; Journal article, 2020)
      Per- and polyfluoroalkyl substances (PFAS) are a class of synthetic organic substances with diverse structures, properties, uses, bioaccumulation potentials and toxicities. Despite this high diversity, all PFAS are alike ...
    • Information Requirements under the Essential-Use Concept: PFAS Case Studies 

      Glüge, Juliane; London, Rachel; Cousins, Ian T.; Dewitt, Jamie; Goldenman, Gretta; Herzke, Dorte; Lohmann, Rainer; Miller, Mark; Ng, Carla A.; Patton, Sharyle; Trier, Xenia; Wang, Zhanyun; Scheringer, Martin (Peer reviewed; Journal article, 2021)
      Per- and polyfluoroalkyl substances (PFAS) are a class of substances for which there are widespread concerns about their extreme persistence in combination with toxic effects. It has been argued that PFAS should only be ...
    • The NORMAN Suspect List Exchange (NORMAN-SLE): facilitating European and worldwide collaboration on suspect screening in high resolution mass spectrometry 

      Mohammed Taha, Hiba; Aalizadeh, Reza; Alygizakis, Nikiforos; Antignac, Jean-Philippe; Arp, Hans Peter; Bade, Richard; Baker, Nancy; Belova, Lidia; Bijlsma, Lubertus; Bolton, Evan E.; Brack, Werner; Celma, Alberto; Chen, Wen-Ling; Cheng, Tiejun; Chirsir, Parviel; Čirka, Ľuboš; D’Agostino, Lisa A.; Djoumbou Feunang, Yannick; Dulio, Valeria; Fischer, Stellan; Gago-Ferrero, Pablo; Galani, Aikaterini; Geueke, Birgit; Głowacka, Natalia; Glüge, Juliane; Groh, Ksenia; Grosse, Sylvia; Haglund, Peter; Hakkinen, Pertti J.; Hale, Sarah; Hernandez, Felix; Janssen, Elisabeth M.-L.; Jonkers, Tim; Kiefer, Karin; Kirchner, Michal; Koschorreck, Jan; Krauss, Martin; Krier, Jessy; Lamoree, Marja H.; Letzel, Marion; Letzel, Thomas; Li, Qingliang; Little, James; Liu, Yanna; Lunderberg, David M.; Martin, Jonathan W.; McEachran, Andrew D.; McLean, John A.; Meier, Christiane; Meijer, Jeroen; Menger, Frank; Merino, Carla; Muncke, Jane; Muschket, Matthias; Neumann, Michael; Neveu, Vanessa; Ng, Kelsey; Oberacher, Herbert; O’Brien, Jake; Oswald, Peter; Oswaldova, Martina; Picache, Jaqueline A.; Postigo, Cristina; Ramirez, Noelia; Reemtsma, Thorsten; Renaud, Justin; Rostkowski, Pawel; Rüdel, Heinz; Salek, Reza M.; Samanipour, Saer; Scheringer, Martin; Schliebner, Ivo; Schulz, Wolfgang; Schulze, Tobias; Sengl, Manfred; Shoemaker, Benjamin A.; Sims, Kerry; Singer, Heinz; Singh, Randolph R.; Sumarah, Mark; Thiessen, Paul A.; Thomas, Kevin V; Torres, Sonia; Trier, Xenia; van Wezel, Annemarie P.; Vermeulen, Roel C. H.; Vlaanderen, Jelle J.; von der Ohe, Peter C.; Wang, Zhanyun; Williams, Antony J.; Willighagen, Egon L.; Wishart, David S.; Zhang, Jian; Thomaidis, Nikolaos S.; Hollender, Juliane; Slobodnik, Jaroslav; Schymanski, Emma L. (Peer reviewed; Journal article, 2022)
      Background The NORMAN Association (https://www.norman-network.com/) initiated the NORMAN Suspect List Exchange (NORMAN-SLE; https://www.norman-network.com/nds/SLE/) in 2015, following the NORMAN collaborative trial on ...
    • An overview of the uses of per- And polyfluoroalkyl substances (PFAS) 

      Glüge, Juliane; Scheringer, Martin; Cousins, Ian T.; Dewitt, Jamie C.; Goldenman, Gretta; Herzke, Dorte; Lohmann, Rainer; Ng, Carla A.; Trier, Xenia; Wang, Zhanyun (Peer reviewed; Journal article, 2020)
      Per- and polyfluoroalkyl substances (PFAS) are of concern because of their high persistence (or that of their degradation products) and their impacts on human and environmental health that are known or can be deduced from ...
    • Strategies for grouping per- and polyfluoroalkyl substances (PFAS) to protect human and environmental health 

      Cousins, Ian T.; DeWitt, Jamie C.; Glüge, Juliane; Goldenman, Gretta; Herzke, Dorte; Lohmann, Rainer; Miller, Mark; Ng, Carla A.; Scheringer, Martin; Vierke, Lena; Wang, Zhanyun (Peer reviewed; Journal article, 2020)
      Grouping strategies are needed for per- and polyfluoroalkyl substances (PFAS), in part, because it would be time and resource intensive to test and evaluate the more than 4700 PFAS on the global market on a chemical-by-chemical ...
    • The concept of essential use for determining when uses of PFASs can be phased out 

      Cousins, Ian T.; Goldenman, G.; Herzke, Dorte; Lohmann, Rainer; Miller, Mark; Ng, Carla A.; Patton, Sharyle; Scheringer, Martin; Trier, Xenia; Vierke, Lena; Wang, Zhanyun; DeWitt, Jamie (Journal article; Peer reviewed, 2019)
      Because of the extreme persistence of per- and polyfluoroalkyl substances (PFASs) and their associated risks, the Madrid Statement argues for stopping their use where they are deemed not essential or when safer alternatives ...
    • Zürich Statement on Future Actions on Per- and Polyfluoroalkyl Substances (PFASs) 

      Ritscher, Amélie; Wang, Zhanyun; Scheringer, Martin; Boucher, Justin M.; Ahrens, Lutz; Berger, Urs; Bintein, Sylvain; Bopp, Stephanie K.; Borg, Daniel; Buser, Andreas M.; Cousins, Ian; DeWitt, Jamie; Fletcher, Tony; Green, Christopher; Herzke, Dorte; Higgins, Christopher; Huang, Jun; Hung, Hayley; Knepper, Thomas; Lau, Christopher S.; Leinala, Eeva; Lindstrom, Andrew B.; Liu, Jinxia; Miller, Mark; Ohno, Koichi; Perkola, Noora; Shi, Yali; Haug, Line Småstuen; Trier, Xenia; Valsecchi, Sara; van der Jagt, Katinka; Vierke, Lena (Others, 2018)
      Per- and polyfluoroalkyl substances (PFASs) are man-made chemicals that contain at least one perfluoroalkyl moiety, –CnF2n–. To date, over 4,000 unique PFASs have been used in technical applications and consumer products, ...