• Do cytotoxicity and cell death cause false positive results in the in vitro comet assay? 

      Azqueta, Amaya; Stopper, Helga; Zegura, Bojana; Dusinska, Maria; Møller, Peter (Peer reviewed; Journal article, 2022)
      The comet assay is used to measure DNA damage induced by chemical and physical agents. High concentrations of test agents may cause cytotoxicity or cell death, which may give rise to false positive results in the comet ...
    • Minimum Information for Reporting on the Comet Assay (MIRCA): recommendations for describing comet assay procedures and results 

      Møller, Peter; Azqueta, Amaya; Boutet-Robinet, Elisa; Koppen, Gudrun; Bonassi, Stefano; Milic, Mirta; Gajski, Goran; Costa, Solange; Teixeira, João Paulo; Pereira, Cristiana Costa; Dusinska, Maria; Godschalk, Roger; Brunborg, Gunnar; Gutzkow, Kristine Bjerve; Giovannelli, Lisa; Cooke, Marcus S.; Richling, Elke; Laffon, Blanca; Valdiglesias, Vanessa; Basaran, Nursen; Del Bo, Cristian; Zegura, Bojana; Novak, Matjaz; Stopper, Helga; Vodicka, Pavel; Vodenkova, Sona; de Andrade, Vanessa Moraes; Srámková, Monika; Gábelová, Alena; Collins, Andrew Richard; Langie, Sabine A.S. (Peer reviewed; Journal article, 2020)
      The comet assay is a widely used test for the detection of DNA damage and repair activity. However, there are interlaboratory differences in reported levels of baseline and induced damage in the same experimental systems. ...